MIMIC: A Multi-centre cohort study evaluating the role of Inflammatory Markers In patient’s presenting with acute ureteric Colic

Service Evaluation Project 

A multi-centre service evaluation of the management of patients presenting with acute ureteric Colic (MIMIC)


Admission to A&E is very common with over 750,000 patients admitted every year in the EU. Current practice in admitting and managing this condition is not clearly known.

Aim and Objective

We would like to assess the intervention rates of patients who are admitted with acute ureteric colic and assess which tests are commonly done in their work up. Of interest is what role clinicians give to inflammatory markers in their management of patients and what imaging tests and interventions were carried out.


Multi-centre national service evaluation in a 1000 patients who have previously been admitted with acute ureteric colic will have data recorded of the date of their first CT scan, the admission details including blood test results and follow up details including whether intervention or imaging was carried out. This is to be collected for patients who have already been managed by their hospital team and whose details are already stored in the trust imaging system and electronic records.

The project meets the criteria for as a service evaluation project as per the HRA online tool (see attachment below) and has also been evaluated by the R&D department at University College London Hospital and deemed as non-research.

This service evaluation will be carried out at a number of hospital sites. It is hoped that observing intervention practice and looking at variation in practice between sites may help us identify areas for service improvement.  

Local Hospital Trust data management policies will be followed. No patient identifiable data will leave the original site. If any communications containing patient identifiable information are deemed necessary they will only be conducted via nhs.net email accounts or Trust email accounts.

Primary Aims

  • To examine whether or not there is any evidence of regional variation within the UK in the proportion of acute ureteric colic patients who undergo intervention.

Additional Aim

  • To determine the level of association, if any, between white blood cell count (WBC count) and subsequent intervention in patients who present with acute ureteric colic.

Deliverables for Audit Departments

In patients admitted with ureteric colic:

  • Intervention rate
  • Intervention type
  • Timing
  • Inflammatory marker levels at presentation

Pilot has been completed

Approved by 6 Audit Departments and carried out in 120 Patients from 6 UK Centers

·      Taimur Shah                     Whittington Hospital, London
·      Veeru Kasivisvanathan     University College Hospital, London
·      Ben Lamb                          University College Hospital, London
·      Sophia Cashman               Peterborough City Hospital, Cambridgeshire
·      Karl Pang                           Sheffield Teaching Hospitals, Sheffield
·      Marcus Cumberbatch       Sheffield Teaching Hospitals, Sheffield
·      Arjun Nambiar                  Cumberland Infirmary, Cumbria
·      James Akman                   St Bartholemew’s Hospital, London

Full launch planned at over 20 sites on 12th September 2016
Data collection will continue till 31st December

Please email: taimur.shah@doctors.org.uk if you would like to be involved

Further Information:
Redcap User Guide
Registration Documents